Amikacin EP Impurity G ·X HCl CAS 50896-99-6(Free Base)

Purity >90%In StockPharmacopoeial Impurity Standards
CAS No.50896-99-6(Free Base)
Molecular FormulaC22H43N5O13
Molecular WeightN/A
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Amikacin EP Impurity G ·X HCl CAS 50896-99-6(Free Base) chemical structure

Description

The occurrence of Amikacin EP Impurity G ·X HCl is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Amikacin EP Impurity G ·X HCl (CAS 50896-99-6(Free Base)) is a certified pharmaceutical impurity reference standard with the molecular formula C22H43N5O13x(HCl) and a molecular weight of 622.07 g/mol.

Amikacin EP Impurity G ·X HCl (C22H43N5O13x(HCl)) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Amikacin EP Impurity G ·X HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC22H43N5O13 x(HCl)
Molecular Weight622.07 g/mol
Purity>90%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
Halogen ContentCl-containing
Nitrogen Atoms5

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